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Crystallin AB antibody
Alpha(B)-crystallin
Heat shock protein beta-5 (HspB5)
Renal carcinoma antigen NY-REN-27
Rosenthal fiber component
Gene name: CRYAB, CRYA2
Heat shock protein beta-5 (HspB5)
Renal carcinoma antigen NY-REN-27
Rosenthal fiber component
Gene name: CRYAB, CRYA2
Out of stock
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00030389
Crystallin AB (CryAB) is a developmentally regulated small heat shock protein known to protect cells from stress damage.It may also play an important role in the Golgi reorganization during cell division.CryAB is known to be associated with a number of neurodegenerative pathologies such as Alzheimer disease amd multiple sclerosis. As well, it has been found to be expressed in breast tumors of patients with shorter survival, suggesting that it may be a useful marker in identifying aggressive breast cancer.
| ID Covalab | pab50222 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide made to a C-terminal region of the human Crystallin AB protein (within residues 100-175) |
| Activity cross reaction | Reacts with human and mouse CRYAB protein. May cross react with rat, sheep, rabbit, monkey, hamster, cow, and pig proteins (100% sequence homology). |
| Species | Hu, Ms |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.1% |
| Storage instructions | Store at 4°C. Do not freeze. |
| Target | Alpha-crystallin B chain |
| Antibody / Antigen | pep50030 |
| Uniprot ID | P02511 |
| Gene ID | 1410 |
| Applications | WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: WB 0.5-1 ug/ml |
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