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F12 / Factor XII antibody
F12, Coagulation factor xii, F12 deficiency, Factor XII, Factor XII deficiency, HAE3, HAEX, HAF, Hageman factor
As low as
€543.40
In stock
Ref
00028675
Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
| ID Covalab | pab75326 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Isotype | IgG |
| Raised in | Goat |
| Immunogen | Activated human Factor XII (F XIIa) purified from plasma. |
| Activity cross reaction | Reacts with human F12 / Factor XII. Specific for Factor XII as demonstrated by immunodiffusion. A single precipitin arc was obtained with normal plasma and no reaction was observed with F. XII-deficient plasma. |
| Species | Hu |
| Labelling | None |
| Form | Purified |
| Preservative | None |
| Storage instructions | Long term: -20°C, Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Target | F12 / Factor XII |
| Uniprot ID | P00748 |
| Applications | ELISA, IHC - P, IP |
| Working dilutions | IHC-P (5 µg/ml) |
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