BCL2 / Bcl-2 (11C5) antibody

B-cell CLL/lymphoma 2, B-cell lymphoma protein 2, Bcl-2, PPP1R50
Gene name: BCL2
Out of stock
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
More Information
ID Covalab mab71374
Product type Primary antibodies
Clonality Monoclonal antibody
Clone 11C5
Isotype IgG2a / Kappa
Raised in Mouse
Immunogen Recombinant human protein purified from E. coli (His-Bcl-2).
Activity cross reaction Reacts with human BCL2 / Bcl-2.
Species Hu
Labelling None
Form Purified
Preservative 0.03% NaN3
Storage instructions Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Target Apoptosis regulator Bcl-2
Uniprot ID P10415
Gene ID 596
Applications ELISA, IHC - P, IP, WB
Working dilutions ELISA, IHC-P (1:100), IP, WB (1:2000)
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