SIRT1 (7B7) antibody

NAD-dependent protein deacetylase sirtuin-1, hSIRT1
Regulatory protein SIR2 homolog 1
SIR2-like protein 1, hSIR2
SirtT1 75 kDa fragment, 75SirT1
Gene name: SIRT1, SIR2L1
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NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression.
More Information
ID Covalab mab70724
Product type Primary antibodies
Clonality Monoclonal antibody
Clone 7B7
Isotype IgG1 / Kappa
Raised in Mouse
Immunogen Human SIRT1 (AAH12499, 456 a.a. ~ 555 a.a) partial recombinant protein with GST tag.
Activity cross reaction Reacts with human SIRT1.
Species Hu
Labelling None
Form Purified (protein A)
Preservative None
Storage instructions +4°C or -20°C, Avoid repeated freezing and thawing.
Target SIRT1
Uniprot ID Q96EB6
Gene ID 23411
Applications ELISA, IF, IHC - P, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ELISA, IF (10 µg/ml), IHC - P (5 µg/ml), WB
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