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SIRT1 (C-Terminus) antibody
NAD-dependent protein deacetylase sirtuin-1, hSIRT1
Regulatory protein SIR2 homolog 1
SIR2-like protein 1, hSIR2
SirtT1 75 kDa fragment, 75SirT1
Gene name: SIRT1, SIR2L1
Regulatory protein SIR2 homolog 1
SIR2-like protein 1, hSIR2
SirtT1 75 kDa fragment, 75SirT1
Gene name: SIRT1, SIR2L1
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00025719
NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression.
| ID Covalab | pab74907 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Isotype | IgG |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide from human SIRT1. |
| Activity cross reaction | Reacts with the C-terminus part of human SIRT1. |
| Species | Hu |
| Labelling | None |
| Form | Purified |
| Preservative | 0.09% NaN3 |
| Storage instructions | Store at 4°C. Do not freeze. |
| Target | SIRT1 |
| Uniprot ID | Q96EB6 |
| Gene ID | 23411 |
| Applications | IHC - P, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC - P (1:50) |
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