We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Human fibrinogen is a complex ~340kD hetero-hexameric (di-trimeric) glycoprotein consisting of 3 pairs of alpha, beta and gamma chains linked by a series of 29 disulphide bonds. The six chains are arranged in such a way that all the N-Terminal ends adjoin to form a central with two trimeric coiled coil structures connecting to outer D domains. Fibrinogen plays an important role in the coagulation process with the D and E domains interacting via the C-Terminal ends of the alpha chains during fibrin clot cross-linking.
| ID Covalab | pab74558 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Isotype | IgG |
| Raised in | Sheep |
| Immunogen | Human Fibrinogen purified from plasma. |
| Activity cross reaction | Reacts with human Fibrinogen. Cross reacts with mouse and rat protein. This antibody shows minimal cross-reactivity with related serum proteins |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | NaN3 0.09% |
| Storage instructions | +4°C or -20°C, Avoid repeated freezing and thawing. Store undiluted. |
| Target | Fibrinogen |
| Applications | ELISA, IF, IHC - F, IHC - P |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: ELISA (1:50 - 1:100), IHC-P (5 µg/ml) |
Write Your Own Review