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BCL2L11 / BIM (Internal) antibody
Bcl-2-like protein 11, Bcl2-L-11, Bcl2-interacting mediator of cell death, BAM, BIM-alpha6, BIM-beta6, BIM-beta7, BimEL, BimL, BOD
Gene name: BCL2L11, BIM
Gene name: BCL2L11, BIM
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00016015
Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.
| ID Covalab | pab70412 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide from internal region of human BCL2L11 / BIM. |
| Activity cross reaction | Reacts with a peptide corresponding to amino acids near the center of human Bim. Cross reacts with mouse and rat due to sequence identity. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Target | BCL2L11 / BIM |
| Uniprot ID | O43521 |
| Gene ID | 10018 |
| Applications | ICC, IHC - P, WB |
| Working dilutions | Optimal dilution to be determined by the researcher IHC - P (5 µg/ml), WB (2.5 µg/ml) |
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