ATG7 (N-Terminus) antibody

Ubiquitin-like modifier-activating enzyme ATG7
ATG12-activating enzyme E1 ATG7
Autophagy-related protein 7 (APG7-like) (hAGP7)
Ubiquitin-activating enzyme E1-like protein
APG7-LIKE, DKFZp434N0735, GSA7
Gene name: ATG7, APG7L
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Functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. Forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. Also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3
More Information
ID Covalab pab70357
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide from N-terminal part of human ATG7.
Activity cross reaction Reacts with 17 amino acid peptide from near the amino terminus of human APG7.
Species Hu, Ms
Labelling None
Form Antigen affinity purified
Preservative NaN3 0.02%
Storage instructions Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Target ATG7
Uniprot ID O95352
Gene ID 10533
Applications ICC, IHC - P, WB
Working dilutions ICC, IHC - P (5 µg/ml), WB (1 - 2 µg/ml)
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