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ATG16L1 (Internal) antibody
Autophagy-related protein 16-1
APG16-like 1
Gene name: ATG16L1, APG16L, ATG16A, ATG16L, FLJ00045, FLJ10035, FLJ10828, FLJ22677, IBD10, WDR30
APG16-like 1
Gene name: ATG16L1, APG16L, ATG16A, ATG16L, FLJ00045, FLJ10035, FLJ10828, FLJ22677, IBD10, WDR30
As low as
€548.90
In stock
Ref
00015825
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
| ID Covalab | pab70354 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | 18 amino acid peptide from near the center of human ATG16. |
| Activity cross reaction | Reacts with ATG16L1 from human, mouse and rat |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Target | ATG16L1 |
| Uniprot ID | Q676U5 |
| Gene ID | 55054 |
| Applications | ELISA, ICC, IF, IHC - P, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC - P 5 µg/ml, WB 0.25 - 0.5 µg/ml ICC 2 µg/ml, IF 4 µg/ml |
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