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AICDA (C-Terminus) antibody
Activation-induced cytidine deaminase
Cytidine aminohydrolase
Gene name : AICDA, AID
ARP2, CDA2, HIGM2
Cytidine aminohydrolase
Gene name : AICDA, AID
ARP2, CDA2, HIGM2
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00015770
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation
| ID Covalab | pab70299 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide from human AICDA. |
| Activity cross reaction | Reacts with peptide corresponding to 14 amino acids near the carboxy-terminus of human AID |
| Species | Hu, Ms |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Target | AICDA |
| Accession Number | Q9GZX7 |
| Applications | ICC, IHC - P, WB |
| Working dilutions | ICC, IHC - P (5 µg/ml), WB (1 - 2 µg/ml) |
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