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Adiponectin (C-Terminus) antibody
Adiponectin
30 kDa adipocyte complement-related protein
Adipocyte complement-related 30 kDa protein (ACRP30)
Adipocyte, C1q and collagen domain-containing protein
Adipose most abundant gene transcript 1 protein (apM-1)
Gelatin-binding protein
Gene name : ADIPOQ, ACDC, ACRP30, APM1, GBP28
ADIPQTL1, ADPN, APM1, GBP28
30 kDa adipocyte complement-related protein
Adipocyte complement-related 30 kDa protein (ACRP30)
Adipocyte, C1q and collagen domain-containing protein
Adipose most abundant gene transcript 1 protein (apM-1)
Gelatin-binding protein
Gene name : ADIPOQ, ACDC, ACRP30, APM1, GBP28
ADIPQTL1, ADPN, APM1, GBP28
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00015743
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
ID Covalab | pab70272 |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Raised in | Rabbit |
Immunogen | Synthetic peptide from human ADIPOQ / Adiponectin. |
Activity cross reaction | Reacts with 15 amino acid peptide from near the carboxy-terminus of human adiponectin |
Species | Hu, Ms, Rat |
Labelling | None |
Form | Antigen affinity purified |
Preservative | NaN3 0.02% |
Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Target | Adiponectin |
Accession Number | Q15848 |
Applications | IHC - P, WB |
Working dilutions | IHC - P (2.5 µg/ml), WB (1 µg/ml) |
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