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Atrial natriuretic factor (ANF/NPPA) antibody
Atrial natriuretic factor (ANF)
Atrial natriuretic peptide (ANP)
Gene name: NPPA, ANP, PND
Atrial natriuretic peptide (ANP)
Gene name: NPPA, ANP, PND
As low as
€278.30
In stock
Ref
00014190
Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
| ID Covalab | pab0507 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide derived from Cter domain of human ANF protein |
| Activity cross reaction | Reacts with human 17 kDa ANF protein clived from Natriuretic peptides A. Cross react with proteins from mouse, rat and other species due to sequence homology. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Antiserum |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Atrial natriuretic factor (ANF/NPPA) |
| Uniprot ID | P01160 |
| Applications | ELISA, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : - IHC : 1/50 to 1/200 - WB: 1/100 to 1/1000 |
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