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HLA-DR antibody (L243)
DLA DRBB1 beta chain
class II invariant chain
Gene : CD74 / DHLAG / DLA-DRB1
class II invariant chain
Gene : CD74 / DHLAG / DLA-DRB1
As low as
€330.00
In stock
Ref
00124748
HLA-DR antibody (L243)
ID Covalab | mab0297-p |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | L243 |
Isotype | IgG2a kappa |
Raised in | Mouse |
Immunogen | Human B lymphocytes |
Activity cross reaction | HLA-DR antibody (L243) recognizes specifically an extracellular epitope on HLA-DR molecules, both peptide-loaded and empty. Cross reacts= Non-Human Primates, Canine (Dog). |
Species | Human |
Labelling | None |
Form | Purified (protein A) |
Preservative | None |
Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
Target | HLA-DR Antibody (L243) is a mouse monoclonal IgG2a kappa light chain antibody engineered to recognize the nonpolymorphic HLA-DR epitope 1-3 on human B lymphocytes. Known also as human leukocyte antigen DR or MHC class II DR, HLA-DR plays a pivotal role in the immune system by presenting antigenic peptides to CD4+ T helper cells, thereby initiating and regulating immune responses essential for pathogen defense and immune surveillance. HLA-DR antibody (L243) exhibits exclusive reactivity with HLA-DR molecules, ensuring no cross-reactivity with HLA-DQ or HLA-DP, which enhances precision in various immunological assays. |
Uniprot ID | (Human) P04233 |
Applications | FC, IF, IHC |
Working dilutions | Optimal dilution should be determined by the end user. |
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