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Anti-4-Hydroxy-2-hexenal Mouse Antibody
4-Hydroxy-2-hexenal (4-HHE), 4-Hydroxy-2-hexenal, 4-HHE, MG, MG-modified protein, 4-Hydroxy-2-hexenal-modified , 4-Hydroxy-2-hexenal, 4-hydroxy Hexenal, HHE, 4-HHE
As low as
€731.00
In stock
Ref
00123901
Lipid peroxidation occurs when oxidizing agents attack carbon-carbon double bonds found in unsaturated lipids. In addition to membrane degradation, oxidation end-products have been found to damage cell viability through their mutagenic and toxic properties. These downstream functional consequences facilitate the development of disease and premature aging. 4-hydroxy-2-hexenal (4-HHE) is a major alpha,beta-unsaturated aldehyde product of n-3 PUFA oxidation resulting from lipid peroxidation. High levels of HHE are found in disease states (1). 4-HHE reacts with histidine residues to form Michael-addition type adducts.
ID Covalab | mab60824 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | 6F10 |
Isotype | IgG2b |
Raised in | Mouse |
Immunogen | Synthetic 4-Hydroxy-2-hexenal modified Keyhole Limpet Hemocyanin (KLH). |
Activity cross reaction | Specific for 4-Hydroxy-2-hexenal (4-HHE) and 4-Hydroxynonenal (4-HNE) modified proteins. Does not detect free 4-Hydroxy-2-hexenal (4-HHE) or 4-Hydroxynonenal (4-HNE). Does not cross-react with Acrolein, Crotonaldehyde, Hexanoyl Lysine, Malondialdehyde, or Methylglyoxal modified proteins. |
Species | Species Independent |
Form | Purified |
Preservative | 0.09% Sodium azide |
Storage instructions | This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. |
Target | 4-Hydroxy-2-hexenal |
Applications | ELISA, FACS, FCM, ICC/IF, WB |
Working dilutions | WB (1:1000); ICC/IF (1:50); ELISA (1:1000); FACS (1:50); FCM (1:50); optimal dilutions for assays should be determined by the user. |
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