Anti-Hexanoyl-Lysine adduct Mouse Antibody

Hexanoyl-Lysine adduct, HEL (Hexanoyl-Lysine adduct), HEL, HEL Adduct, Hexanoyl-Lys adduct, Hexanoyl-Lys, Hexanoyl-Lysine (HEL) adduct, Hexanoyl-Lys (HEL), Hexanoyl Lysine adduct, Hexanoyl-Lysine adduct-modified protein, Hexanoyl-Lysine Adduct (HEL)
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Hexanoyl-lysine adduct (HEL) is a lysine adduct of 13-HPODE and is produced by the oxidation of omega-6 polyunsaturated fatty acids (1). It is a biomarker for the initial stage of lipid peroxidation. Lipid peroxidation end-products have been found to damage cell viability through their mutagenic and toxic properties. These downstream functional consequences facilitate the development of disease and premature aging.
More Information
ID Covalab mab60823
Product type Primary antibodies
Clonality Monoclonal antibody
Clone 5E8
Isotype IgG1
Raised in Mouse
Immunogen Synthetic Hexanoyl modified Keyhole Limpet Hemocyanin (KLH).
Activity cross reaction Specific for Hexanoyl-Lysine adduct (HEL) modified peptides and proteins. Does not detect free Hexanoyl-Lysine. Does not cross-react with Acrolein, Crotonaldehyde, 4-Hydroxy-2-hexenal, 4-Hydroxy nonenal, Malondialdehyde, or Methylglyoxal modified proteins.
Species Species Independent
Form Purified
Preservative 0.09% Sodium azide
Storage instructions This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
Target Hexanoyl-Lysine adduct
Applications ELISA, FACS, FCM, ICC/IF, WB
Working dilutions WB (1:1000); ICC/IF (1:50); ELISA (1:1000); FACS (1:50); FCM (1:50); optimal dilutions for assays should be determined by the user.
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