Anti-Dibromo-tyrosine Mouse Antibody

3,5-Dibromo-tyrosine, 3,5-dibromotyrosine, Dibromotyrosine, Dibromo-tyrosine, DiBrY, Dibromotyrosine (DiBrY), Dibromo-Tyrosine (DiBrY), Dibromo-tyrosine [DiBrY]
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00123897
Dibromotyrosine is a major product of protein oxidation due to oxidative stress. Neutrophil myeloperoxidase (MPO) and eosinophil peroxidase (EPO), enzymes expressed in granulocytes, catalyze the formation of hypobromous acid (HOBr) from hydrogen peroxide (H2O2) and bromide ion (Br-). HOBr reacts with tyrosine residues in proteins to produce 3, 5-dibromotyrosine. (1)
More Information
ID Covalab mab60820
Product type Primary antibodies
Clonality Monoclonal antibody
Clone 6G3
Isotype IgG1
Raised in Mouse
Immunogen Synthetic 3,5-Dibromotyrosine conjugated to Keyhole Limpet Hemocyanin (KLH).
Activity cross reaction Specific for 3,5-Dibromo-tyrosine. Does not cross-react with Nitrotyrosine.
Species Species Independent
Form Purified
Preservative 0.09% Sodium azide
Storage instructions This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
Target Dibromo-tyrosine
Applications ELISA, ICC/IF, IHC, WB
Working dilutions WB (1:1000); ICC/IF (1:50); ELISA (1:1000); IHC (1:100); optimal dilutions for assays should be determined by the user.
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