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Anti-Acrolein Mouse Antibody
Acrolein modified protein, Acrolein conjugated protein, 2-Propen-1-one, 2-propenal, Acraldehyde, Acrolein, Acrylic aldehyde, Protein-bound Acrolein
As low as
€731.00
In stock
Ref
00123896
Lipid peroxidation occurs when oxidizing agents attack carbon-carbon double bonds found in unsaturated lipids. In addition to membrane degradation, oxidation end-products have been found to damage cell viability through their mutagenic and toxic properties. These downstream functional consequences facilitate the development of disease and premature aging. Acrolein is an electrophilic conjugated aldehyde that is a terminal product of lipid peroxidation. Acrolein is highly mutagenic and reacts with nucleophilic functional groups in DNA and proteins such as cysteine, histidine, and lysine residues (1).
| ID Covalab | mab60819 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 10A10 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Synthetic Acrolein modified Keyhole Limpet Hemocyanin (KLH). |
| Activity cross reaction | Specific for Acrolein modified proteins. Does not detect free acrolein. Does not cross-react with Crotonaldehyde, Hexanoyl Lysine, 4-Hydroxy-2-hexenal, 4-Hydroxy nonenal, Malondialdehyde, or Methylglyoxal modified proteins. |
| Species | Species Independent |
| Form | Purified |
| Preservative | 0.09% Sodium azide |
| Storage instructions | This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | Acrolein |
| Applications | ELISA, FACS, FCM, ICC/IF, WB |
| Working dilutions | WB (1:1000); ICC/IF (1:50); FACS (1:50); FCM (1:50); ELISA (1:1000); IHC (1:100); optimal dilutions for assays should be determined by the user. |
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