CD1d antibody (51.1)

Antigen-presenting glycoprotein CD1d
R3G1
CD1d
Gene name: CD1D
As low as €337.00
In stock
Ref
00122068
CD1d belongs to CD1 family of transmembrane glycoproteins, associated with beta2 microglobulin, similarly to MHC I molecules. Unlike other CD1 family members, however, CD1d can be also expressed in a non-glycosylated form, which is not associated with beta2 microglobulin. Hence it is not certain how much CD1d plays a role in the presentation of microbial lipid antigens during infection. On the other hand, it is expressed on various antigen presenting cell types. Besides it, CD1d+ thymocytes are involved in the positive selection of sublineage of NKT cells.
More Information
ID Covalab mab21338
Product type Primary antibodies
Clonality Monoclonal antibody
Clone 51.1
Isotype IgG2b kappa
Raised in Mouse
Immunogen The mouse monoclonal antibody 51.1 recognizes an extracellular epitope of CD1d, a 38 kDa transmembrane glycoprotein expressed mainly on cortical thymocytes, marginal zone B cells and other antigen presenting cells, but also i e.g. hepatitis C virus-infected livers.
Species Hu, Mk
Labelling None
Form Purified (protein A)
Preservative NaN3 15 mM
Storage instructions Store at 2-8°C. Do not freeze.
Target CD1D
Uniprot ID P15813
Gene ID 912
Applications FC, IHC-F, IP, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
FC (4-8 µg/ml)
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