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CD1d antibody (51.1)
Antigen-presenting glycoprotein CD1d
R3G1
CD1d
Gene name: CD1D
R3G1
CD1d
Gene name: CD1D
As low as
€370.70
In stock
Ref
00122068
CD1d belongs to CD1 family of transmembrane glycoproteins, associated with beta2 microglobulin, similarly to MHC I molecules. Unlike other CD1 family members, however, CD1d can be also expressed in a non-glycosylated form, which is not associated with beta2 microglobulin. Hence it is not certain how much CD1d plays a role in the presentation of microbial lipid antigens during infection. On the other hand, it is expressed on various antigen presenting cell types. Besides it, CD1d+ thymocytes are involved in the positive selection of sublineage of NKT cells.
| ID Covalab | mab21338 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 51.1 |
| Isotype | IgG2b kappa |
| Raised in | Mouse |
| Immunogen | The mouse monoclonal antibody 51.1 recognizes an extracellular epitope of CD1d, a 38 kDa transmembrane glycoprotein expressed mainly on cortical thymocytes, marginal zone B cells and other antigen presenting cells, but also i e.g. hepatitis C virus-infected livers. |
| Species | Hu, Mk |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | NaN3 15 mM |
| Storage instructions | Store at 2-8°C. Do not freeze. |
| Target | CD1D |
| Uniprot ID | P15813 |
| Gene ID | 912 |
| Applications | FC, IHC-F, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : FC (4-8 µg/ml) |
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