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Integrin alpha-6 (ITGA6) antibody (GoH3)
Integrin alpha-6
CD49 antigen-like family member F
VLA-6
CD49f
Gene name: ITGA6
CD49 antigen-like family member F
VLA-6
CD49f
Gene name: ITGA6
As low as
€407.80
In stock
Ref
00122064
CD49f (alpha 6 integrin) is a type I transmembrane glycoprotein, which noncovalently associates with CD29 (beta 1 integrin) to form VLA-6, and with CD104 (beta 4 integrin) to form alpha6/beta4 integrin complex. CD49f is expressed on platelets, megakaryocytes, monocytes, T cells and thymocytes. It is widely expressed on many cultured adherent cell lines and on epithelia in non-lymphoid tissues. It is important for adhesion to laminins, invasin, and merosin, hence also for cell migration, embryogenesis, metastasis, formation of hemidesmosomes in epithelia, and other processes.
ID Covalab | mab21336 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | GoH3 |
Isotype | IgG2a |
Raised in | Rat |
Immunogen | The rat monoclonal antibody GoH3 recognizes an extracellular epitope of CD49f, an alpha6 integrin subunit. |
Species | Cat, Cow, Dog, Hs, Hu, Mk, Ms, Pig, Rb, Shp |
Labelling | None |
Form | Purified (protein G) |
Preservative | NaN3 15 mM |
Storage instructions | Store at 2-8°C. Do not freeze. |
Target | ITGA6 |
Uniprot ID | P23229 |
Gene ID | 3655 |
Applications | FC, ICC, IHC-F, IP |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : FC (1-4 µg/ml) |
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