CD272 antibody (MIH26)

B- and T-lymphocyte attenuator
B- and T-lymphocyte-associated protein
CD272
Gene name: BTLA
As low as €321.30
In stock
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00119458
CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.
More Information
ID Covalab mab21326
Product type Primary antibodies
Clonality Monoclonal antibody
Clone MIH26
Isotype IgG2a kappa
Raised in Mouse
Immunogen The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272, a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.
Species Hu
Labelling None
Form Purified (protein A)
Preservative NaN3 15 mM
Storage instructions Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
Target BTLA
Uniprot ID Q7Z6A9
Applications FC
Working dilutions Optimal dilution should be determined by the end user.
FC (2-5 µg/ml)
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