CD235a antibody (JC159) [Biotin]

Glycophorin-A
MN sialoglycoprotein
PAS-2
Sialoglycoprotein alpha
CD235a
Gene name: GYPA, GPA
As low as €413.00
In stock
Ref
00119301
CD235a (Glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to glycophorin B (GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, an Streptococcus adhesin.
More Information
ID Covalab mab21324
Product type Primary antibodies
Clonality Monoclonal antibody
Clone JC159
Isotype IgG1
Raised in Mouse
Immunogen The mouse monoclonal antibody JC159 recognizes an epitope between amino acids 27 and 40 of the extracellular portion of CD235a (glycophorin A), a sialoglycoprotein expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL. The antibody does not react with glycophorin B.
Activity cross reaction Membrane preparation from splenic hairy cell leukemia
Species Hu, Rat
Labelling Biotin
Form Purified
Preservative NaN3 15 mM
Storage instructions Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
Target CD235a
Uniprot ID P02724
Gene ID 2993
Applications FC, IHC-F, IHC-P
Working dilutions Optimal dilution should be determined by the end user.
FC (1-4 µg/ml)
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