CD235a (Glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to glycophorin B (GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, an Streptococcus adhesin.
|Product type||Primary antibodies|
|Immunogen||The mouse monoclonal antibody JC159 recognizes an epitope between amino acids 27 and 40 of the extracellular portion of CD235a (glycophorin A), a sialoglycoprotein expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL. The antibody does not react with glycophorin B.|
|Activity cross reaction||Membrane preparation from splenic hairy cell leukemia|
|Preservative||NaN3 15 mM|
|Storage instructions||Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.|
|Applications||FC, IHC-F, IHC-P|
|Working dilutions||Optimal dilution should be determined by the end user.
FC (1-4 µg/ml)
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