Alpha-Tubulin antibody (YOL1/34)

Tubulin alpha-1A chain
Alpha-tubulin 3
Tubulin B-alpha-1
Tubulin alpha-3 chain
Gene name: TUBA1A, TUBA3
As low as €337.00
In stock
The microtubules are intracellular dynamic polymers made up of evolutionarily conserved polymorphic alpha/beta-tubulin heterodimers and a large number of microtubule-associated proteins (MAPs). The microtubules consist of 13 protofilaments and have an outer diameter 25 nm. Microtubules are also necessary for movement of cells by means of flagella and cilia. In mammalian tissue culture cells microtubules have their minus ends anchored in microtubule organizing centers (MTOCs). The alpha-tubulin (relative molecular weight around 50 kDa) is globular protein that exists in cells as part of soluble alpha/beta-tubulin dimer or it is polymerized into microtubules. In different species it is coded by multiple tubulin genes that form tubulin classes (in human 6 genes). Expressed tubulin genes are named tubulin isotypes. Some of the tubulin isotypes are expressed ubiquitously, while some have more restricted tissue expression. Alpha-tubulin is also subject of numerous post-translation
More Information
ID Covalab mab21322
Product type Primary antibodies
Clonality Monoclonal antibody
Clone YOL1/34
Isotype IgG2a
Raised in Rat
Immunogen The rat monoclonal antibody YOL1/34 recognizes an epitope of alpha-tubulin localized between amino acids 414-422. It has higher affinity for fixed microtubules than for native ones.
Activity cross reaction Yeast tubulin
Species Hu, Ms, Rat, Yeast
Labelling None
Form Purified (protein A)
Preservative NaN3 15 mM
Storage instructions Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
Target Alpha-Tubulin
Uniprot ID Q71U36
Gene ID 7277
Applications ELISA, FC, ICC, IHC, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC (4-8 µg/ml)
WB (1-2 µg/ml)
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