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Ganglioside-OacGD3 antibody (7H2)
As low as
€219.00
In stock
Ref
00012723
Useful for monitoring gangliosides in ELISA, TLC and immunoblotting.
| ID Covalab | mab0015 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 7H2 |
| Isotype | IgG3 / Kappa |
| Raised in | Mouse |
| Immunogen | Ganglioside-OAcGD3 |
| Activity cross reaction | Reacts with OAcGD3 ganglioside : OAcNeuAc alpha 2-8NeuAc alpha 2-3Gal beta 1-4Glc beta 1-1Cer. |
| Species | All Sp. |
| Labelling | None |
| Form | Cell culture supernatant |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Ganglioside-OAcGD3 |
| Applications | ELISA, TLC |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : - ELISA : 1/5 to 1/50 - TLC : 1/5 to 1/20 |
| Publication | Cerato E. et al. Variable region gene segments of nine monoclonal antibodies specific todisialogangliosides (GD2, GD3) and their O-acetylated derivatives. Hybridoma (1997), 16(4),307-316. Thomas C.P. et al. Gangliosides protect human melanoma cells from ionizing radiationinduced clonogenic cell death. Glycoconj. J. (1996), 13(3), 377-384. Zebda N. et al. Deficiency of ganglioside biosynthesis in metastatic human melanoma cells: relevance of CMP-NeuAc:LacCer alpha 2-3 sialyltransferase (GM3 synthase). FEBS Letters (1995), 362(2), 161-164. Portoukalian J. et al. Shedding of GD2 ganglioside in patients with retinoblastoma. Int. J.Cancer (1993), 53(6), 948-951. |
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