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Fatty Acid Synthase (FAS) antibody
Fatty acid synthase
Including the following 7 domains:
1. [Acyl-carrier-protein] S-acetyltransferase
2. [Acyl-carrier-protein] S-malonyltransferase
3. 3-oxoacyl-[acyl-carrier-protein] synthase
4. 3-oxoacyl-[acyl-carrier-protein] reductase
5. 3-hydroxyacyl-[acyl-carrier-protein] dehydratase
6. Enoyl-[acyl-carrier-protein] reductase
7. Oleoyl-[acyl-carrier-protein] hydrolase
Gene name: FASN, Fasn
Including the following 7 domains:
1. [Acyl-carrier-protein] S-acetyltransferase
2. [Acyl-carrier-protein] S-malonyltransferase
3. 3-oxoacyl-[acyl-carrier-protein] synthase
4. 3-oxoacyl-[acyl-carrier-protein] reductase
5. 3-hydroxyacyl-[acyl-carrier-protein] dehydratase
6. Enoyl-[acyl-carrier-protein] reductase
7. Oleoyl-[acyl-carrier-protein] hydrolase
Gene name: FASN, Fasn
As low as
€480.40
In stock
Ref
00096466
FAS (Fatty Acid Synthase) is a central enzyme in de novo lipogenesis (triglyceride production).It is a target for SREBP and is upregulated by LXR activation.Fatty liver is often the result of FAS activation.It is also one of the accepted markers for insulin resistance and SREBP, LXR activation.
| ID Covalab | pab50029 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | An internal synthetic peptide, conjugated to KLH, made near the N-terminus of the mouse FAS protein sequence. |
| Activity cross reaction | Reacts with FAS protein from human, pig, rat, mouse, primate, chicken and plants. |
| Species | Chick, Hu, Mk, Ms, Pl, Po, Rat |
| Labelling | None |
| Form | Antiserum |
| Preservative | NaN3 0.05% |
| Storage instructions | Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
| Target | Fatty Acid Synthase |
| Uniprot ID | P19096 |
| Applications | ICC, IF, IHC, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: ICC/IF (1:2000) IHC (1:500) IP (1:100) WB (1:1000) |
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