Eukaryotic translation initiation factor 3 subunit E (eIF3e) antibody

Eukaryotic translation initiation factor 3 subunit E, eIF3e
Eukaryotic translation initiation factor 3 subunit 6
Viral integration site protein INT-6 homolog
eIF-3 p48
Gene name : EIF3E, EIF3S6, INT6
As low as €294.00
In stock
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00012575
Belongs to the eIF-3 subunit E family. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.
More Information
ID Covalab pab0857-P
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Partial recombinant human eIF3e protein (N terminal part) FLAG-Tagged
Activity cross reaction Reacts with human eIF3e protein.
Species Hu
Labelling None
Form Purified (protein A)
Preservative None
Storage instructions Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target Eukaryotic translation initiation factor 3 subunit E
Uniprot ID P60228
Applications IF, WB
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only :
IF (1:100 - 1:1000)
WB (1:500 - 1:2000)
Publication * Neusiedler J et al. INT6 interacts with MIF4GD/SLIP1 and is necessary for efficient histone mRNA translation. RNA. 2012 Jun,18(6):1163-77. (IF, WB)
* Morris C, et al. INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells. Cancer Res. 2012 Apr 15,72(8):2006-16. (IF)
* Morris-Desbois C, et al. Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies. J Cell Sci. 1999 Oct,112 ( Pt 19):3331-42.
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