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FGFR1 antibody (M17D10)
Fibroblast Growth Factor Receptor 1 (FGFR1)
FGFR-1
Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1
Fms-like tyrosine kinase 2, FLT-2
N-sam
Proto-oncogene c-Fgr
CD_antigen : CD331
CEK, FLG, HH2
OGD, KAL2, HBGFR, HRTFDS
Gene name : FGFR1
FGFR-1
Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1
Fms-like tyrosine kinase 2, FLT-2
N-sam
Proto-oncogene c-Fgr
CD_antigen : CD331
CEK, FLG, HH2
OGD, KAL2, HBGFR, HRTFDS
Gene name : FGFR1
As low as
€480.40
In stock
Ref
00096685
Fibroblast Growth Factor Receptor 1 (FGFR1) is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. This protein is a Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration.
| ID Covalab | mab60172 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | M17D10 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Recombinant human ectodomain of FGFr1β expressed in E. coli from pro23 to his415, antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH-terminal glu-phe sequences. |
| Activity cross reaction | Reacts with human FGFR1. Epitope is within the sequence pro179 to lys195 in Ig loop II. |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | 0.02% |
| Storage instructions | Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles. |
| Target | FGFR1 |
| Uniprot ID | P11362 |
| Gene ID | 2260 |
| Applications | ICC, IHC, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : ICC (1:100) IHC (5 µg/ml) WB (1 µg/ml) |
| Publication | * Robinson ML, et al.Development. 1995 Dec,121(12):3959-67. (WB, Hu) * Xu J, et al. J Biol Chem. 1992 Sep 5,267(25):17792-803. |
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