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LC3B antibody
Microtubule-associated proteins 1A/1B light chain 3B
Autophagy-related protein LC3 B
Autophagy-related ubiquitin-like modifier LC3 B
MAP1 light chain 3-like protein 2
MAP1A/MAP1B light chain 3 B, MAP1A/MAP1B LC3 B
Microtubule-associated protein 1 light chain 3 beta
Gene name: MAP1LC3B, MAP1ALC3
Autophagy-related protein LC3 B
Autophagy-related ubiquitin-like modifier LC3 B
MAP1 light chain 3-like protein 2
MAP1A/MAP1B light chain 3 B, MAP1A/MAP1B LC3 B
Microtubule-associated protein 1 light chain 3 beta
Gene name: MAP1LC3B, MAP1ALC3
As low as
€480.40
In stock
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00030609
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
| ID Covalab | pab50206 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide made to an N-terminal portion of the human LC3B protein sequence (between residues 1-100) |
| Activity cross reaction | Reacts with LC3B from human, mouse, rat, bacteria, bovin, syrian hamster, porcine and zebrafish. |
| Species | Ba, Bov, Hu, Ms, Rat, Zfi |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.05% |
| Storage instructions | Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
| Target | LC3B |
| Uniprot ID | Q9GZQ8 |
| Gene ID | 81631 |
| Applications | FC, ICC, IF, IHC, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : WB (0.5 - 2 µg/ml) ICC/IF (1:200) IHC 1(:200 - 1:400) IP (20 µg/500 µg of protein) |
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