E3 ubiquitin-protein ligase TRIM22 antibody

50 kDa-stimulated trans-acting factor
RING finger protein 94
Staf-50
Tripartite motif-containing protein 22
Gene name: TRIM22, RNF94, STAF50
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00014373
Interferon-induced antiviral protein involved in cell innate immunity. The antiviral activity could in part be mediated by TRIM22-dependent ubiquitination of viral proteins. Plays a role in restricting the replication of HIV-1, encephalomyocarditis virus (EMCV) and hepatitis B virus (HBV). Acts as a transcriptional repressor of HBV core promoter.
More Information
ID Covalab pab0631-P
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide derived from an internal domain of human TRIM22
Activity cross reaction Reacts with human 57 kDa Staf-50. May cross react with proteins from other species due to sequence homology
Species Hu
Labelling None
Form Purified (protein A)
Preservative None
Storage instructions Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target E3 ubiquitin-protein ligase TRIM22
Uniprot ID Q8IYM9
Applications ELISA, IHC, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/500
- WB : 1/200 to 1/2 000
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