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Estrogen-related receptor alpha antibody
Steroid hormone receptor ERR1
Estrogen receptor-like 1
Nuclear receptor subfamily 3 group B member 1
Gene name: ESRRA, ERR1, ESRL1, NR3B1
Estrogen receptor-like 1
Nuclear receptor subfamily 3 group B member 1
Gene name: ESRRA, ERR1, ESRL1, NR3B1
As low as
€480.40
In stock
Ref
00101467
Estrogen-related receptor alpha (ERR alpha) is an orphan member of the superfamily of nuclear hormone receptors. It was initially isolated based on its sequence homology to the estrogen receptor but is not activated by classic estrogens. ERR alpha preferentially binds to an ERR alpha response element (ERRE) containing a single consensus half-site, TNAAGGTCA. ERR alpha can control the expression of MCAD through the NRRE-1 and thus may play an important role in regulating cellular energy balance in vivo.
| ID Covalab | pab52602 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide made to an N-terminal portion of the human protein (within residues 1-50). [Swiss-Prot# P11474] |
| Activity cross reaction | Reacts with human and mouse ESRRA protein. May cross react with rat, pig and dog (100% sequence homology). |
| Species | Ca, Hu, Ms, Po, Rat |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.1% |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Estrogen-related receptor alpha (ERR-alpha) |
| Uniprot ID | P11474 |
| Gene ID | 2101 |
| Applications | ICC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : - ICC : 1/100 - WB : 2.0 µg/ml |
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