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Park7 / DJ-1 antibody
Oncogene DJ1
Parkinson disease protein 7
Gene name: PARK7
Parkinson disease protein 7
Gene name: PARK7
As low as
€480.40
In stock
Ref
00099303
Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.
ID Covalab | pab50148 |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Raised in | Rabbit |
Immunogen | Synthetic peptide corresponding to the C-terminus (within residues 150-189) of human Park7(DJ-1). |
Activity cross reaction | Reacts with human and mouse Protein DJ-1. May cross react with rat, bovine, Zebra fish, Golden hamster and chicken proteins (100% sequence homology). |
Species | Hu, Ms |
Labelling | None |
Form | Antiserum |
Preservative | None |
Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
Target | Protein DJ-1 |
Uniprot ID | Q99497 |
Gene ID | 11315 |
Applications | FA, ICC, IF, IP, WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : ICC 1:500 IP 1:200 WB 1:2 000 |
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