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HIF-1 alpha hP564 peptide
HIF-1 alpha Hydroxyproline 564
Hypoxia-inducible factor 1-alpha, HIF-1-alpha, HIF1-alpha
ARNT-interacting protein
Basic-helix-loop-helix-PAS protein MOP1
Class E basic helix-loop-helix protein 78, bHLHe78
Member of PAS protein 1
PAS domain-containing protein 8
Gene name: HIF1A, BHLHE78, MOP1, PASD8
Hypoxia-inducible factor 1-alpha, HIF-1-alpha, HIF1-alpha
ARNT-interacting protein
Basic-helix-loop-helix-PAS protein MOP1
Class E basic helix-loop-helix protein 78, bHLHe78
Member of PAS protein 1
PAS domain-containing protein 8
Gene name: HIF1A, BHLHE78, MOP1, PASD8
As low as
€249.30
In stock
Ref
00096277
Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters.
| ID Covalab | pep0396 |
|---|---|
| Product type | Peptides |
| Target domain | surrounding P564 |
| Activity cross reaction | This peptide blocks completely the immuno reactivity of the antibody pab0396 in WB or IHC by incubating the peptide with equivalent volume of antibody for 30 min at 37 °C. |
| Species | Hu |
| Labelling | None |
| Antibody / Antigen | pab0396 |
| Preservative | NaN3 0.02 % |
| Storage instructions | Shipment at 4°C. Upon arrival, aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. |
| Target | HIF-1 alpha Hydroxyproline 564 |
| Uniprot ID | Q16665 |
| Gene ID | 3091 |
| Description | WB, ELISA |
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