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ADAMTS4 (Metalloprotease Domain) antibody
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAM-TS 4) (ADAM-TS4) (ADAMTS-4)
ADMP-1
Aggrecanase-1
Gene name : ADAMTS4, KIAA0688
ADAMTS-2
ADMP-1
Aggrecanase-1
Gene name : ADAMTS4, KIAA0688
ADAMTS-2
As low as
€521.40
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00015651
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
ID Covalab | pab70258 |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Raised in | Rabbit |
Immunogen | Synthetic 16 amino acid peptide from Metalloprotease domain of human ADAMTS4. Percent identity with other species by BLAST analysis: Human (100%), Orangutan (100%), Gibbon (100%), Marmoset (100%), Panda (100%), Dog (100%), Bat (100%), Horse (100%) |
Activity cross reaction | Reacts with human ADAMTS4. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Species | Hu |
Labelling | None |
Form | Antigen affinity purified |
Preservative | NaN3 0.1% |
Storage instructions | Long term: -70°C; Short term: +4°C |
Target | ADAMTS4 |
Accession Number | O75173 |
Applications | IHC - P |
Working dilutions | IHC - P (4 ) |
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