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BAG1 (2D3) antibody
BAG family molecular chaperone regulator 1 (BAG-1)
Bcl-2-associated athanogene 1
BAG1, Bcl2 binding protein bag1, HAP, RAP46
Bcl-2-associated athanogene 1
BAG1, Bcl2 binding protein bag1, HAP, RAP46
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00027682
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity. Markedly increases the anti-cell death function of BCL2 induced by various stimuli.
| ID Covalab | mab71139 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 2D3 |
| Isotype | IgG2a / Kappa |
| Raised in | Mouse |
| Immunogen | Human BAG1 (NP_004314, 241 a.a. ~ 346 a.a) partial recombinant protein with GST tag. |
| Activity cross reaction | Reacts with human BAG1. Cross reacts with mouse and rat protein. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Target | BAG1 |
| Applications | ELISA, IF, IHC - P, WB |
| Working dilutions | ELISA, IF (35 µg/ml), IHC-P (10 µg/ml), WB (1:500 - 1:1000) |
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