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X-Ray Repair Cross-Complementing Group 3 (XRCC3) antibody

X-ray repair cross-complementing protein 3
Gene name: XRCC3
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C. Involved in Breast cancer.

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Ref : 00029068

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Product Code pab50082
Immunogen Synthetic partial peptide of human XRCC3
Target Specificity Reacts with human 38 kDa XRCC3 protein. Not reacts in mouse. No cross-reactivity with XRCC2, RAD51, RAD51B, RAD51C, or RAD51D. Not tested in other species.
Name DNA repair protein XRCC3
Uniprot ID O43542
Gene ID 7517
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.05%
Storage Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Applications Western Blot, Immunoprecipitation
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/5 000
Positive control HeLa
Research areas Cancer,Chromatin,Nuclear signaling
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WB: XRCC3 antibody<br/>Anti-XRCC3 antibody WB staining of (1) HTC116 and (2)  Hela whole cell extracts, .<br/> Antibody pab50082 dilution 1:2500.

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