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Cardiac Troponin I antibody (19C7)

Troponin I, cardiac muscle
Troponin I Type 3 (cardiac)
Cardiac troponin I
Gene name : TNNI3, TNNC1
Belongs to the troponin I family.
Defects in TNNI3 are the cause of familial hypertrophic cardiomyopathy type 7 (CMH7), familial restrictive cardiomyopathy type 1 (RCM1), cardiomyopathy dilated type 2A (CMD2A) and cardiomyopathy dilated type 1FF (CMD1FF).

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Ref : 00036370

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Product Code mab50147
Clone 19C7
Immunogen Native troponin complex, (epitope 41-49 aa)
Target Specificity Reacts with protein from Human, Mouse, Rat, Bovine, Canine, Feline, Fish, Goat, Porcine and Rabbit.
Equally reactive with free cardiac troponin I (cTnI) and cTnI forming complexes with other troponin components. (In the presence of 5 mM EDTA). Antibodies are not affected by heparin, phosphorylation, oxidation and troponin complex formation. No cross-reaction with skeletal muscle troponin I.
Name Troponin I, cardiac muscle
Uniprot ID P19429
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Product type Primary antibodies
Clonality Monoclonal antibody
Isotype IgG2b
Produced in Mouse
Species Human, Mouse, Rat, Other
Labelling None
Appearance Liquid
Form Purified (protein A)
Constituents PBS, (pH 7.4)
Preservatives NaN3 0.1%
Storage Short term storage at +4°C. Do not freeze
Applications Western Blot, Immunohistochemistry, Flow Cytometry, ELISA, Immunoprecipitation
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
WB 1:100-1:2000
IHC 1:10-1:500
IP 1:10-1:500
Sandwich ELISA 1:100-1:2000
Research areas Cardiac and vascular biomarkers,Disease-related biomarkers,Signal transduction
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Immunoassay: Cardiac Troponin I antibody (19C7)<br/>(mab50147)<br/>Cardiac Troponin I antibody (19C7) recognized dephospho-(light blue 19C7) and biphospho-(dark blue 22B11) forms of cTnl.

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