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Transcription factor E2F1 acetyl-lysine 120 and 125 (E2F-1) antibody

PBR3
PRB-binding protein E2F-1
Retinoblastoma-associated protein 1 (RBAP-1)
Retinoblastoma-binding protein 3 (RBBP-3)
Gene name: E2F1, RBBP3
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis.

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Product Code pab0726
Immunogen Synthetic peptide derived from internal domain of human E2F-1 protein containing acetyl lysine 120 and 125
Target Specificity Reacts with human E2F-1 acK120 and acK125. May cross-react with E2F-1 from mouse and other species due to sequence homology
Name Transcription factor E2F1 acetyl-lysine 120 and 125 (E2F-1)
Uniprot ID Q01094
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse
Labelling None
Appearance Lyophilized powder
Form Antiserum
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunohistochemistry, ELISA
Working dilutions Optimal dilutions should be determined by the end user.
Research areas Cancer,Chromatin,Nuclear signaling
Print datasheet

Transcription factor E2F1 acetyl-lysine 120 and 125 (E2F-1) antibody

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