Close Forward an order
By clicking this button, you can send a message to your purchasing manager to ask her/him to order this product. All information needed about our company and the product will be automatically attached. You will also have the opportunity to ask us for more information about the product. If so, your request will be forwarded to our technical service.

Captcha

* Required Fields

Back to products list

p53 (N-Terminus) antibody

Cellular tumor antigen p53
Antigen NY-CO-13
Phosphoprotein p53
Tumor suppressor p53
Gene name: TP53, P53
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription.

If you want to order offline

orders@covalab.com - tel: +33 (0) 437 654 230 - fax: +33 (0) 437 289 416

€360.00
Available
Ref : 00023623

* Required Fields

Product Code pab74269
Immunogen Synthetic peptide from aa6-55 of human p53.
Target Specificity Reacts with the N-terminus part of human TP53 / p53. Cross reacts with rat protein.
Name TP53 / p53
Uniprot ID P04637
Gene ID 7157
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS (without Mg2+, Ca2+), pH 7.4, NaCl 150 mM, glycerol 50%
Preservatives NaN3 0.02%
Storage Store at -20°C for up to one year.
Applications Western Blot, IHC - Paraffin sections, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ELISA (1:10000), IHC-P (10 µg/ml), WB (1:500 - 1:1000)
Research areas Autophagy
Print datasheet

IHC : p53 (N-Terminus) antibody<br/>(pab74269)<br/>Anti-p53 antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab74269 concentration 10 µg/ml.

Newsletter Receive news, promotions and offers in your e-mail box