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Survival motor neuron protein antibody (SCB3)

Survival motor neuron protein
Component of gems 1
Gemin-1
Gene name : SMN1, SMN, SMNT, SMN2, SMNC
The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs.

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Product Code mab0061-P
Clone SCB3
Immunogen GST-SMN fusion protein
Target Specificity Reacts with human SMN1 in various human foetal tissues.
Name Survival motor neuron protein
Uniprot ID Q16637
Gene ID 6606
Print datasheet
Product type Primary antibodies
Clonality Monoclonal antibody
Isotype IgG1 / Kappa
Produced in Mouse
Species Human
Labelling None
Appearance Lyophilized powder
Conc. / Activity 1 mg/ml
Form Purified (protein A)
Constituents PBS
Preservatives NaN3 0.02%
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunofluorescence, ELISA, Immunoprecipitation
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IF (1:500 - 1:2000)
IP (1:50 - 1:200)
WB (1:500 - 1:2000)
ELISA (1:1000 - 1:5000)
Research areas Apoptosis,Neurology
Print datasheet
- Lefebvre S, et al. Identification and characterization of a spinal muscular atrophy-determining gene. Cell. 80, 155-165.
- Burlet, P. et al. The distribution of SMN protein complex in human fetal tissues and its alteration in Spinal Muscular atrophy

Survival motor neuron protein antibody (SCB3)

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