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SIRT2 (N-Terminus) antibody

NAD-dependent protein deacetylase sirtuin-2
Regulatory protein SIR2 homolog 2
SIR2-like protein 2
Gene name: SIRT2, SIR2L, SIR2L2
NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and non-histone proteins such as ACLY, PCK1 and RELA. Deacetylates 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton. Deacetylates PCK1, opposing proteasomal degradation. Deacetylates 'Lys-310' of RELA.

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€360.00
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Ref : 00021486

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Product Code pab73213
Immunogen 17 amino acid peptide near the amino terminus of the human SIRT2.
Target Specificity Reacts with human, mouse and rat SIRT2.
Name SIRT2
Uniprot ID Q8IXJ6
Gene ID 22933
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.02%
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Applications Western Blot, IHC - Paraffin sections, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC-P (5 µg/ml),
WB (2.5 - 5 µg/ml)
Research areas Autophagy,Cancer,Chromatin,Inflammation,Post translational modifications
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IHC - SIRT2 (N-Terminus) antibody<br/>(pab73213)<br/>Anti-SIRT2 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab73213 concentration 5 ug/m

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