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SIRT2 (C-Terminus) antibody

NAD-dependent protein deacetylase sirtuin-2
Regulatory protein SIR2 homolog 2
SIR2-like protein 2
Gene name: SIRT2, SIR2L, SIR2L2
NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and non-histone proteins such as ACLY, PCK1 and RELA. Deacetylates 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton. Deacetylates PCK1, opposing proteasomal degradation. Deacetylates 'Lys-310' of RELA.

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Ref : 00021485

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Product Code pab73212
Immunogen 19 amino acid peptide near the carboxy terminus of the human SIRT2.
Target Specificity Reacts with the C-terminus part of human SIRT2. Cross reacts with mouse and rat protein.
Name SIRT2
Uniprot ID Q8IXJ6
Gene ID 22933
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.02%
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Applications Western Blot, IHC - Paraffin sections, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC-P (5 µg/ml),
WB (1 - 2 µg/ml)
Research areas Autophagy,Cancer,Cell metabolism,Chromatin,Inflammation,Post translational modifications
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IHC : SIRT2 (C-Terminus) antibody<br/>(pab73212)<br/>Anti-SIRT2 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab73212 concentration 5 ug/m

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