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SIRT1 (C-Terminus) antibody

NAD-dependent protein deacetylase sirtuin-1, hSIRT1
Regulatory protein SIR2 homolog 1
SIR2-like protein 1, hSIR2
SirtT1 75 kDa fragment, 75SirT1
Gene name: SIRT1, SIR2L1
NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression.

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€360.00
Available
Ref : 00025719

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Product Code pab74907
Immunogen Synthetic peptide from human SIRT1.
Target Specificity Reacts with the C-terminus part of human SIRT1.
Name SIRT1
Uniprot ID Q96EB6
Gene ID 23411
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Form Purified
Constituents PBS, pH 7.2, 50% glycerol
Preservatives 0.09% NaN3
Storage Store at 4°C. Do not freeze.
Applications Western Blot, IHC - Paraffin sections, Immunoprecipitation
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC - P (1:50)
Research areas Apoptosis,Autophagy,Cell cycle,Cell metabolism,Chromatin,Post translational modifications
Print datasheet

IHC : SIRT1 (C-Terminus) antibody<br/>(pab74907)<br/>Anti-SIRT1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab74907 dilution 1:50.

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