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SIRT1 (7B7) antibody

NAD-dependent protein deacetylase sirtuin-1, hSIRT1
Regulatory protein SIR2 homolog 1
SIR2-like protein 1, hSIR2
SirtT1 75 kDa fragment, 75SirT1
Gene name: SIRT1, SIR2L1
NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression.

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€410.00
Available
Ref : 00027063

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Product Code mab70724
Clone 7B7
Immunogen Human SIRT1 (AAH12499, 456 a.a. ~ 555 a.a) partial recombinant protein with GST tag.
Target Specificity Reacts with human SIRT1.
Name SIRT1
Uniprot ID Q96EB6
Gene ID 23411
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Product type Primary antibodies
Clonality Monoclonal antibody
Isotype IgG1 / Kappa
Produced in Mouse
Species Human
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Purified (protein A)
Constituents PBS, pH 7.2
Preservatives None
Storage +4°C or -20°C, Avoid repeated freezing and thawing.
Applications Western Blot, IHC - Paraffin sections, Immunofluorescence, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ELISA, IF (10 µg/ml), IHC - P (5 µg/ml), WB
Research areas Apoptosis,Autophagy,Cell cycle,Cell metabolism,Chromatin,Post translational modifications
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IHC : SIRT1(7B7) antibody<br/>(mab70724)<br/>Anti-SIRT1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody mab70724 concentration 5 ug/ml.

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