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Serine/threonine-protein kinase LATS2 antibody

Serine/threonine-protein kinase LATS2
Kinase phosphorylated during mitosis protein
Large tumor suppressor homolog 2
Serine/threonine-protein kinase kpm
Warts-like kinase
Gene name : LATS2, KPM
Negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

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Price From: €165.00
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Product Code pab0891-P
Immunogen LATS2 tagged partial recombinant protein
Target Specificity Reacts with human LATS2 protein
Name Serine/threonine-protein kinase LATS2
Uniprot ID Q9NRM7
Gene ID 26524
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Lyophilized powder
Conc. / Activity 1 mg/ml
Form Purified (protein A)
Constituents Tris 0,1M, glycine 0,1M, sucrose 2%
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunofluorescence, ELISA
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB 1:500 - 1:5000
IF 1:200 - 1:1000
Research areas Cancer,Hippo core,Hippo pathway,Kinases and phosphatases,Nuclear signaling
Print datasheet
Boin A et al. Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas. Neuro Oncol. 2014 Feb 20.

IF : Serine/threonine-protein kinase LATS2 antibody<br/>(# pab0891-P)<br/>Anti-Serine/threonine-protein kinase LATS2 antibody IF staining of HeLa cells transfected with Serine/threonine-protein kinase LATS2. Antibody pab0891-P dilution 1/500.

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