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SEMA4D antibody

CD_antigen: CD100
Gene name: SEMA4D, C9orf164, CD100, SEMAJ
Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.

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Ref : 00036343

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Product Code pab51040
Immunogen Synthetic peptide corresponding to residues 777-788 [KPKSDFCDREQS] of the human CD100 protein.
Target Specificity Reacts with human CD100.
Uniprot ID Q92854
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.02%
Storage Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
WB (1:100 - 1:2000)
Research areas Immunology
Print datasheet

WB - SEMA4D antibody<br/>(pab51040)<br/>Anti-SEMA4D antibod WB staining of CHO transfected cells. Antibody dilution 1:500.

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