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SCN9A / Nav1.7 (Internal) antibody

Sodium channel protein type 9 subunit alpha
Neuroendocrine sodium channel, hNE-Na
Peripheral sodium channel 1, PN1
Sodium channel protein type IX subunit alpha
Voltage-gated sodium channel subunit alpha Nav1.7
Gene name: SCN9A, PN1, ETHA, NENA, SFNP, FEB3B, NE-NA, GEFSP7, Nav1.7
This sodium channel is involved in the development of inflammatory pain.

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Ref : 00021450

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Product Code pab73177
Immunogen Synthetic 17 amino acid peptide from internal region (aa460-510) of human SCN9A / Nav1.7. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Monkey (100%), Marmoset (94%), Mouse (94%), Panda (94%), Dog (94%)
Target Specificity Reacts with SCN9A from Human, Gorilla, Gibbon. Predicted to cross react with Monkey, Mouse, Bovine, Dog, Horse, Pig, Rabbit (>90% homology). BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SCN8A (71%).
Name SCN9A / Nav1.7
Uniprot ID Q15858
Gene ID 6335
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.1%
Storage Long term: -70°C; Short term: +4°C
Applications IHC - Paraffin sections
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
IHC-P (10 µg/ml)
Research areas Ion channels,Neurology,Signal transduction
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IHC : SCN9A / Nav1.7 (Internal) antibody<br/>(pab73177)<br/>Anti-SCN9A / Nav1.7 antibody IHC of human small intestine, neuroendocrine cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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