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Rad17 antibody

Gene name: RAD17
Signals originating from damaged DNA activate checkpoint pathways and target the mitotic apparatus via a number a distinct mechanisms.These checkpoints link damage to DNA with the components of the cell cycle through signal transduction systems.
In mammals, five genes have been identified as components of DNA damage-induced checkpoint pathways: ATM, p53, p21/WAF1/CIP1, hCHK1, and 14-3-3sigma.When overexpressed in mammalian cells, hRAD17 activates p53 and causes an accumulation of G1 phase cells, suggesting an involvement of the hRAD17 gene in this checkpoint pathway.

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€335.00
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Ref : 00029082

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Product Code pab50509
Immunogen Synthetic peptide made to a N-terminal region of human RAD17.
Target Specificity Reacts with human Rad17
Name Rad17
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Form Purified
Constituents PBS
Preservatives NaN3 0.01%
Storage Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Flow Cytometry
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/1 000
Research areas Cell cycle,Nuclear signaling
Print datasheet

WB: Rad17 antibody<br/>(pab50509)<br/>Anti-Rad17 antibody WB staining of heart lysate.

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