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Rad17 antibody

Gene name: RAD17
Signals originating from damaged DNA activate checkpoint pathways and target the mitotic apparatus via a number a distinct mechanisms.These checkpoints link damage to DNA with the components of the cell cycle through signal transduction systems.
In mammals, five genes have been identified as components of DNA damage-induced checkpoint pathways: ATM, p53, p21/WAF1/CIP1, hCHK1, and 14-3-3sigma.When overexpressed in mammalian cells, hRAD17 activates p53 and causes an accumulation of G1 phase cells, suggesting an involvement of the hRAD17 gene in this checkpoint pathway.

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Ref : 00029082

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Product Code pab50509
Immunogen Synthetic peptide made to a N-terminal region of human RAD17.
Target Specificity Reacts with human Rad17
Name Rad17
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Form Purified
Constituents PBS
Preservatives NaN3 0.01%
Storage Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Flow Cytometry
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/1 000
Research areas Cell cycle,Nuclear signaling
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WB: Rad17 antibody<br/>(pab50509)<br/>Anti-Rad17 antibody WB staining of heart lysate.

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