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Pyruvate dehydrogenase kinase (PDK1) antibody

Pyruvate dehydrogenase kinase, PDK1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial
Pyruvate dehydrogenase kinase isoform 1, PDH kinase 1
Gene name: PDK1, PDHK1
Pyruvate dehydrogenase kinase isoform 1 (PDK1) inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

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Product Code pab50211
Immunogen Synthetic peptide made to a C-Terminal portion of the human PDK1 protein sequence (between residues 350-436)
Target Specificity Reacts with the human, mouse, rat PDK1. Predicted to cross react with chicken (93%).
Name Pyruvate dehydrogenase kinase, PDK1
Uniprot ID Q15118
Gene ID 5163
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 0,4 mg/ml
Form Purified
Constituents Tris-glycine, NaCl 150mM buffer
Preservatives NaN3 0.05%
Storage Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Applications Western Blot, Immunofluorescence, Immunocytochemistry
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
ICC/IF (1:1000-1:2000)
WB (2 µg/ml)
Research areas Kinases and phosphatases,Signal transduction
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WB - PDK1 antibody<br/>(pab50211)<br/>Anti-PDK1 antibody WB staining of human heart lysate. Antibody dilution 2 µg/ml

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