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Protein phosphatase 1 regulatory subunit 12A antibody

Myosin phosphatase-targeting subunit 1 (Myosin phosphatase target subunit 1)
Protein phosphatase myosin-binding subunit
Gene name : PPP1R12A, MBS, MYPT1
Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.

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Price From: €165.00
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Product Code pab0506-P
Immunogen Synthetic peptide derived from Nter domain of human MYPT1 protein
Target Specificity Reacts with human 115 kDa MYPT1 protein. Cross reacts with proteins from mouse, rat and other species.
Name Protein phosphatase 1 regulatory subunit 12A
Uniprot ID O14974
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Lyophilized powder
Conc. / Activity 1 mg/ml
Form Purified (protein A)
Constituents Tris 0,1M, glycine 0,1M, sucrose 2%
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunohistochemistry, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/200
- WB : 1/100 to 1/1 000
Research areas Kinases and phosphatases,Nuclear signaling,Signal transduction
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Protein phosphatase 1 regulatory subunit 12A antibody

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