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Prokineticin 2 (PK2/Bv8) antibody

Prokineticin-2 (PK2)
Protein Bv8 homolog
Gene name : PROK2, BV8, HH4, KAL4, MIT1
Prokineticins belong to a family of highly conserved small peptides discovered a decade ago in frog skin and snake venon. The mammalian orthologs consist in two prokineticins peptides: prokineticin 1 (PK1) and prokineticin 2 (PK2), signaling through two receptors: prokineticin receptor 1 (PK-R1) and prokineticin receptor 2 (PK-R2).

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Product Code pab0409
Immunogen Synthetic peptide derived from Cter region of human PK2
Target Specificity Reacts with human 14 kDa PK2.Cross reacts with proteins from mouse, rat and other species
Name Prokineticin 2 (PK2)
Uniprot ID Q9HC23
Gene ID 60675
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat, Bovine
Labelling None
Appearance Lyophilized powder
Form Antiserum
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, IHC - Paraffin sections, IHC - Frozen section, Immunocytochemistry, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/ IHC (1:50 - 1:1000)
WB (1:200 - 1:1000)
Research areas Angiogenesis,Cancer,Developmental biology,Inflammation,Neurology
Print datasheet
- Abou-Hamdan M. et al. Critical role for prokineticin 2 in CNS autoimmunity. Neurol Neuroimmunol Neuroinflamm 2015;2:e95 (IHC-F)
- Lauttia S et al. Prokineticins and Merkel cell polyomavirus infection in Merkel cell carcinoma. Br J Cancer. 2014 Feb 4.(IHC-P, Hu)
- Keramidas M et al. Mitogenic functions of endocrine gland-derived vascular endothelial growth factor and Bombina variegata 8 on steroidogenic adrenocortical cells. J Endocrinol. 2008 Mar;196(3):473-82.(IHC-P, ICC, Bov)
- Hoffmann P et al. Expression and oxygen regulation of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 and its receptors in human placenta during early pregnancy. Endocrinology. 2006 Apr:147(4):1675-84. (IHC-P, Hu, Ms)

Prokineticin 2 (PK2/Bv8) antibody

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